The differences between uniCenta oPOS v4 and earlier versions keep growing with each new update.
Here is the list as of 5 January 2016 when it was first released.
Check the CHANGELOG page to see how it has evolved month by month since then.
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    OVERALL

    NEW
    1. Look and Feel
    2. Stock level notification
    3. Multi-Database option – Primary + Secondary
    4. iButton (Dallas key) support
    5. JVM RAM monitor Widget
    6. Stock Maintenance
    7. Service Charge Option
    8. CAS-PDII Weigh Scale support
    9. Mettler weigh scale support
    10. Reprint last Receipt
    11. Add new Customer pop-up within sale
    IMPROVED
    1. Overall performance
    2. Product Finder – with image
    3. Customer Finder – with image
    4. Category and Product load times
    5. Date and Time Clock to DefaultLocale
    6. Legacy Jasper Reports components – now v6
    7. All languages wrapped into run-time
    8. DB schema changes
    9. Configuration settings
    DEPRECATED
    1. Substance/PushingPixels Look and Feel
    2. Databases – Apache Derby, HSQLDB and Oracle
    3. Database – PostgreSQL (temporary – will re-instate EOY)
    4. Stock Diary
    5. 800 x 600 pixels screens
    6. Java JRE 7 support

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    NEW MODULES

    1. Suppliers
    2. Vouchers/Coupons
    3. Products Units Of Measure (UOM)
    4. CloseCash reprint
    5. Stock Maintenance
    6. Web Reporting (separate app’)

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    LANGUAGES

    FULL
    1. English UK – Default
    2. English US
    3. French
    PARTIAL
    1. Albanian
    2. Arabic
    3. Brazilian
    4. Croatian
    5. Dutch
    6. German
    7. Greek
    8. Italian
    9. Portuguese
    10. Spanish – Spain
    11. Spanish – Mexico
    DEPRECATED
    1. Swedish – 95% incomplete

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    CUSTOMER

    NEW
    1. Image in Customer Finder
    2. Flag as VIP
    3. Set a Default Discount
    4. Create Customer popup from within Sales screen
    5. Add new create Customer to current ticket
    IMPROVED
    1. Customer record load time
    2. Customer Product transactions

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    PRODUCT

    NEW
    1. Units Of Measure (UOM)
    2. Assign main Supplier
    3. Create new Supplier pop-up
    4. View a Product’s stock movements
    5. View multi-location Stock
    6. Order in Catalogue
    7. Product Category over-ride
    8. Image in Product Finder
    IMPROVED
    1. Barcode recognition
    2. Assign printer to Product
    3. Button display editor

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    TICKET

    NEW
    1. Lock-out current ticket
    2. 6 x customisable ticket formats
    3. Create New Customer on the fly
    4. Reprint last ticket
    5. Check Product stock position
    6. Cannot refund a Refund
    7. Cannot refund a ticket more than one time
    IMPROVED
    1. Product load time
    2. Customer load time
    3. Remote print only allowed on ticket change
    4. Change and delete permissions
    5. Print and re-Print permissions
    6. User ticket stack
    7. Barcode scanning recognition

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    RESTAURANT

    NEW
    1. Table access lock-out
    2. Multi-part kitchen order print
    3. Ticket change and delete permissions
    4. Print, reprint permissions
    5. Assign number of diners to table
    6. Table plan auto-refresh
    IMPROVED
    1. Ticket change remote print
    2. Reservations form

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    PAYMENT

    NEW
    1. One-time use of Voucher/Coupon
    DEPRECATED
    1. Card payment gateways (PCI compliance)

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    CLOSE CASH

    NEW
    1. Close Cash preview
    2. Reprint previous Close Cash

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    REPORTS

    NEW
    1. Supplier reports
    2. User reports
    IMPROVED
    1. Jasper Reports engine upgrade to version 6
    2. Inventory reports
    3. Sales reports